Physiological and pathophysiological functions of the amyloid precursor protein (APP)
The amyloid precursor protein (APP) is the source of amyloid-beta (Abeta), the small protein whose abnormal deposition in the brain is thought to cause Alzheimer's disease. But APP's normal role has remained elusive, despite years of study. Our group is interested in elucidating the cellular function of the amyloid precursor protein (APP) in health and disease.
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